At a glance
- CAS number
- 52225-20-4
- INCI name
- Tocopheryl Acetate
- Function
- antioxidant, active, emollient
- Typical use level
- 0.1%–1%
- Solubility
- oil
- Stable pH
- 4–8
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
DL-alpha-Tocopherol acetate all-rac-alpha-Tocopheryl acetate (+-)-alpha-Tocopherol acetate Alpha-tocopherol acetate, dl- Tocopheryl Acetate, dl-Alpha Alpha-tocopheryl acetate, dl- Vitamin E acetate dl- RefChem:1083891 Tocopheryl acetate,dl-alpha d,l-alpha-Tocopherol Acetate Tocopheryl acetate Vitamin E acetate
Compatibility
Works well with:
Retinyl Palmitate Niacinamide Hyaluronic Acid Glycerin Dimethicone Jojoba Oil Caprylic/Capric Triglyceride Cetyl Alcohol Shea Butter Panthenol
Use caution with:
L-Ascorbic Acid Strong Oxidizing Agents
Tocopheryl Acetate is the esterified, stabilized form of Vitamin E and is generally well-tolerated across most formulations. High concentrations of L-Ascorbic Acid can potentially compete or interfere in oxidation-reduction dynamics, though this interaction is less pronounced than with free tocopherol. It must be dispersed in the oil phase during formulation as it is not water-soluble.
Formulation notes
Tocopheryl Acetate requires enzymatic hydrolysis to convert to active tocopherol on skin; efficacy as a direct antioxidant in-formula is lower than free tocopherol, but it offers superior stability. EU Cosmetics Regulation permits use without specific concentration restriction at cosmetic levels; typically used at 0.1–1% for antioxidant protection of both formula and skin. Non-irritating and considered safe for leave-on and rinse-off applications.
Frequently asked questions
What is Tocopheryl Acetate?
Tocopheryl Acetate is a antioxidant, active, emollient used in cosmetic and personal-care formulation. Typical use level is 0.1%–1%. It is oil-soluble. Stable in the pH 4–8 range.
What is Tocopheryl Acetate used for?
Tocopheryl Acetate is used as antioxidant, active, emollient in cosmetic and personal-care formulations.
What is the typical use level of Tocopheryl Acetate?
Tocopheryl Acetate is typically used at 0.1%–1% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Tocopheryl Acetate?
The CAS registry number for Tocopheryl Acetate is 52225-20-4. Its INCI name is Tocopheryl Acetate.
At what pH is Tocopheryl Acetate stable?
Tocopheryl Acetate is generally stable in the pH 4–8 range.
What ingredients are compatible with Tocopheryl Acetate?
Tocopheryl Acetate works well with Retinyl Palmitate, Niacinamide, Hyaluronic Acid, Glycerin, Dimethicone, Jojoba Oil, Caprylic/Capric Triglyceride, Cetyl Alcohol, Shea Butter, Panthenol. Use caution when combining it with L-Ascorbic Acid, Strong Oxidizing Agents.
Related ingredients
- TocopherolAntioxidant
- BakuchiolActive
- BisabololActive
- LecithinEmulsifier
- RetinolActive
- Rosehip Seed OilEmollient