At a glance
- CAS number
- 16485-10-2
- INCI name
- Panthenol
- Function
- humectant, emollient, active, hair conditioning
- Typical use level
- 0.1%–5%
- Solubility
- water
- Stable pH
- 4–7.5
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
DL-Panthenol panthenol DL-Pantothenol DL-Pantothenyl alcohol Pantenol Panthenolum Pantenolo Panthenol, racemic 2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide Purple Toner ELF Perm Roota Re F Tonic
Compatibility
Works well with:
Hyaluronic Acid Glycerin Niacinamide Allantoin Betaine Aloe Vera Ceramides Peptides Vitamin E Sodium PCA
Use caution with:
Strong Oxidizing Agents High-concentration AHAs
Panthenol is broadly compatible with most cosmetic ingredients and performs well across a wide range of formulation types. At very low pH (below 4.0), it may undergo hydrolysis to pantothenic acid, reducing efficacy. Strong oxidizing agents can degrade panthenol and should be avoided in combination.
Formulation notes
D-Panthenol (dextrorotatory form) is preferred over DL-Panthenol for maximum biological activity. Commonly used at 0.5–2% in leave-on skin products and 0.1–1% in rinse-off hair care. No significant safety restrictions at typical use levels; well-tolerated and considered non-sensitizing.
Frequently asked questions
What is Panthenol?
Panthenol is a humectant, emollient, active, hair conditioning used in cosmetic and personal-care formulation. Typical use level is 0.1%–5%. It is water-soluble. Stable in the pH 4–7.5 range.
What is Panthenol used for?
Panthenol is used as humectant, emollient, active, hair conditioning in cosmetic and personal-care formulations.
What is the typical use level of Panthenol?
Panthenol is typically used at 0.1%–5% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Panthenol?
The CAS registry number for Panthenol is 16485-10-2. Its INCI name is Panthenol.
At what pH is Panthenol stable?
Panthenol is generally stable in the pH 4–7.5 range.
What ingredients are compatible with Panthenol?
Panthenol works well with Hyaluronic Acid, Glycerin, Niacinamide, Allantoin, Betaine, Aloe Vera, Ceramides, Peptides, Vitamin E, Sodium PCA. Use caution when combining it with Strong Oxidizing Agents, High-concentration AHAs.
Related ingredients
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