At a glance
- CAS number
- 68-26-8
- INCI name
- Retinol
- Function
- active, antioxidant, emollient
- Typical use level
- 0.01%–1%
- Solubility
- oil
- Stable pH
- 4.5–6.5
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
retinol all-trans-Retinol trans-retinol Veroftal Agoncal Bentavit A Homagenets Aoral Sehkraft A Testavol S all-trans-Vitamin A All-trans retinol Super A
Compatibility
Works well with:
Niacinamide Hyaluronic Acid Tocopherol Squalane Ceramides Glycerin Peptides BHT BHA
Use caution with:
L-Ascorbic Acid Benzoyl Peroxide AHAs BHAs Salicylic Acid Hydrogen Peroxide Copper Peptides
Retinol is highly susceptible to oxidative degradation and is destabilized by low-pH acids (e.g., L-Ascorbic Acid, AHAs) and oxidizing agents like benzoyl peroxide, which accelerate its breakdown. Copper peptides may catalyze oxidation of retinol, reducing efficacy. Antioxidants such as Tocopherol (Vitamin E) and BHT are strongly recommended as co-ingredients to protect retinol stability.
Formulation notes
Extremely sensitive to light, heat, and air — must be formulated in opaque, airtight packaging. EU Cosmetics Regulation restricts retinol to 0.3% in face products and 0.05% in body lotions; products should carry a warning advising against use during pregnancy. Incorporate at cool-down phase (below 40°C). Typically encapsulated or solubilized in oil phase for improved stability.
Frequently asked questions
What is Retinol?
Retinol is a active, antioxidant, emollient used in cosmetic and personal-care formulation. Typical use level is 0.01%–1%. It is oil-soluble. Stable in the pH 4.5–6.5 range.
What is Retinol used for?
Retinol is used as active, antioxidant, emollient in cosmetic and personal-care formulations.
What is the typical use level of Retinol?
Retinol is typically used at 0.01%–1% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Retinol?
The CAS registry number for Retinol is 68-26-8. Its INCI name is Retinol.
At what pH is Retinol stable?
Retinol is generally stable in the pH 4.5–6.5 range.
What ingredients are compatible with Retinol?
Retinol works well with Niacinamide, Hyaluronic Acid, Tocopherol, Squalane, Ceramides, Glycerin, Peptides, BHT, BHA. Use caution when combining it with L-Ascorbic Acid, Benzoyl Peroxide, AHAs, BHAs, Salicylic Acid, Hydrogen Peroxide, Copper Peptides.
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