At a glance
- CAS number
- 98-92-0
- INCI name
- Niacinamide
- Function
- active, antioxidant, humectant, skin conditioning
- Typical use level
- 2%–10%
- Solubility
- water
- Stable pH
- 5–7
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
nicotinamide niacinamide 3-Pyridinecarboxamide pyridine-3-carboxamide Nicotinic acid amide Aminicotin Amixicotyn Benicot Dipegyl Papulex Pelonin amide Nicotilamide
Compatibility
Works well with:
Hyaluronic Acid Zinc PCA Peptides Ceramides Panthenol Glycerin Retinol Salicylic Acid Alpha Arbutin Tranexamic Acid
Use caution with:
L-Ascorbic Acid Copper Peptides Acidic AHA/BHA at low pH
Niacinamide can react with L-Ascorbic Acid to form a yellow-tinted nicotinic acid complex (niacin), particularly at elevated temperatures or low pH, reducing efficacy of both actives. Copper peptides may be deactivated when combined with niacinamide due to chelation interference. Highly acidic formulations (pH below 4) can hydrolyze niacinamide to nicotinic acid, causing flushing and instability.
Formulation notes
Well-tolerated at 2–5% for brightening and barrier support; concentrations up to 10% used for sebum control and anti-inflammatory effects. Above 10%, risk of skin flushing increases. Keep formulation pH between 5–7 for optimal stability and to minimize niacin conversion. Considered safe for all skin types including sensitive skin.
Frequently asked questions
What is Niacinamide?
Niacinamide is a active, antioxidant, humectant, skin conditioning used in cosmetic and personal-care formulation. Typical use level is 2%–10%. It is water-soluble. Stable in the pH 5–7 range.
What is Niacinamide used for?
Niacinamide is used as active, antioxidant, humectant, skin conditioning in cosmetic and personal-care formulations.
What is the typical use level of Niacinamide?
Niacinamide is typically used at 2%–10% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Niacinamide?
The CAS registry number for Niacinamide is 98-92-0. Its INCI name is Niacinamide.
At what pH is Niacinamide stable?
Niacinamide is generally stable in the pH 5–7 range.
What ingredients are compatible with Niacinamide?
Niacinamide works well with Hyaluronic Acid, Zinc PCA, Peptides, Ceramides, Panthenol, Glycerin, Retinol, Salicylic Acid, Alpha Arbutin, Tranexamic Acid. Use caution when combining it with L-Ascorbic Acid, Copper Peptides, Acidic AHA/BHA at low pH.
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