At a glance
- CAS number
- 58-08-2
- INCI name
- Caffeine
- Function
- active, antioxidant, skin conditioning
- Typical use level
- 0.5%–3%
- Solubility
- water
- Stable pH
- 4–7
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
caffeine Guaranine 1,3,7-Trimethylxanthine Methyltheobromine Theine Thein Cafeina Caffein Cafipel Koffein Mateina Alert-pep
Compatibility
Works well with:
Niacinamide Hyaluronic Acid Glycerin Panthenol Allantoin Green Tea Extract Retinol Peptides Vitamin E
Use caution with:
Tannic Acid High-concentration Tannins Strong Oxidizing Agents
Caffeine can form insoluble complexes with tannins and polyphenols at higher concentrations, potentially causing precipitation or reduced efficacy. It is generally stable and compatible with most common cosmetic actives across a moderate pH range. Strong oxidizing agents may degrade the xanthine structure over time.
Formulation notes
No specific regulatory maximum in EU cosmetics; typical use is 0.5–3% in eye creams, serums, and slimming products. Solubility in water is approximately 20 mg/mL at room temperature (2%), so formulations above this level may require warming or a co-solvent. No known sensitization concerns at typical use levels.
Frequently asked questions
What is Caffeine?
Caffeine is a active, antioxidant, skin conditioning used in cosmetic and personal-care formulation. Typical use level is 0.5%–3%. It is water-soluble. Stable in the pH 4–7 range.
What is Caffeine used for?
Caffeine is used as active, antioxidant, skin conditioning in cosmetic and personal-care formulations.
What is the typical use level of Caffeine?
Caffeine is typically used at 0.5%–3% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Caffeine?
The CAS registry number for Caffeine is 58-08-2. Its INCI name is Caffeine.
At what pH is Caffeine stable?
Caffeine is generally stable in the pH 4–7 range.
What ingredients are compatible with Caffeine?
Caffeine works well with Niacinamide, Hyaluronic Acid, Glycerin, Panthenol, Allantoin, Green Tea Extract, Retinol, Peptides, Vitamin E. Use caution when combining it with Tannic Acid, High-concentration Tannins, Strong Oxidizing Agents.
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