At a glance
- CAS number
- 97-59-6
- INCI name
- Allantoin
- Function
- active, soothing, keratolytic, skin conditioning, wound healing
- Typical use level
- 0.1%–2%
- Solubility
- water
- Stable pH
- 4–8
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
allantoin 5-Ureidohydantoin Glyoxyldiureide Cordianine Glyoxyldiureid Allantol Sebical Alantan AVC/Dienestrolcream Psoralon Septalan Urea, (2,5-dioxo-4-imidazolidinyl)-
Compatibility
Works well with:
Niacinamide Hyaluronic Acid Panthenol Glycerin Aloe Vera Centella Asiatica Extract Ceramides Peptides Zinc PCA Beta-Glucan
Use caution with:
High concentration Salicylic Acid High concentration L-Ascorbic Acid
Allantoin is generally well-tolerated across most formulation systems. At very low pH (below 4.0), solubility decreases and the molecule can degrade over time, so pairing with high-concentration acidic actives should be done cautiously. It is considered broadly compatible with most cosmetic ingredients and is often used as a calming co-ingredient alongside potentially irritating actives.
Formulation notes
CIR and EU Cosmetics Regulation permit up to 2% in rinse-off and leave-on products. Dissolves slowly in cold water; gentle heating (40–60°C) aids dissolution. Synthesized or derived from urea oxidation; vegan synthetic form widely available. No known sensitization concerns at typical use levels.
Frequently asked questions
What is Allantoin?
Allantoin is a active, soothing, keratolytic, skin conditioning, wound healing used in cosmetic and personal-care formulation. Typical use level is 0.1%–2%. It is water-soluble. Stable in the pH 4–8 range.
What is Allantoin used for?
Allantoin is used as active, soothing, keratolytic, skin conditioning, wound healing in cosmetic and personal-care formulations.
What is the typical use level of Allantoin?
Allantoin is typically used at 0.1%–2% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Allantoin?
The CAS registry number for Allantoin is 97-59-6. Its INCI name is Allantoin.
At what pH is Allantoin stable?
Allantoin is generally stable in the pH 4–8 range.
What ingredients are compatible with Allantoin?
Allantoin works well with Niacinamide, Hyaluronic Acid, Panthenol, Glycerin, Aloe Vera, Centella Asiatica Extract, Ceramides, Peptides, Zinc PCA, Beta-Glucan. Use caution when combining it with High concentration Salicylic Acid, High concentration L-Ascorbic Acid.
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