At a glance
- CAS number
- 9004-65-3
- INCI name
- Hydroxypropyl Methylcellulose
- Function
- thickener, film_former, emulsifier, humectant
- Typical use level
- 0.1%–5%
- Solubility
- water
- Stable pH
- 3–11
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
HPMC Hypromellose Methocel Methylhydroxypropylcellulose Cellulose Hydroxypropyl Methyl Ether
Compatibility
Works well with:
Glycerin Propylene Glycol Carbomer Sodium Hyaluronate Panthenol Niacinamide
Use caution with:
High concentrations of electrolytes Strongly oxidizing agents
HPMC disperses readily in cold water and hydrates upon heating or prolonged mixing; it should not be added to hot water directly as it can form lumps. High salt concentrations can reduce viscosity and may cause salting-out at elevated electrolyte levels. It is generally compatible with a broad range of cosmetic actives and preservatives within its stable pH range.
Formulation notes
Hydroxypropyl Methylcellulose is a semisynthetic cellulose ether widely used in cosmetics as a thickener, film former, and rheology modifier for gels, lotions, and eye drops. It provides a smooth, non-tacky skin feel and forms a flexible film on skin and hair that can improve moisture retention. It is considered low-irritancy, non-ionic, and suitable for sensitive skin formulations.
Frequently asked questions
What is Hydroxypropyl Methylcellulose?
Hydroxypropyl Methylcellulose is a thickener, film_former, emulsifier, humectant used in cosmetic and personal-care formulation. Typical use level is 0.1%–5%. It is water-soluble. Stable in the pH 3–11 range.
What is Hydroxypropyl Methylcellulose used for?
Hydroxypropyl Methylcellulose is used as thickener, film_former, emulsifier, humectant in cosmetic and personal-care formulations.
What is the typical use level of Hydroxypropyl Methylcellulose?
Hydroxypropyl Methylcellulose is typically used at 0.1%–5% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Hydroxypropyl Methylcellulose?
The CAS registry number for Hydroxypropyl Methylcellulose is 9004-65-3. Its INCI name is Hydroxypropyl Methylcellulose.
At what pH is Hydroxypropyl Methylcellulose stable?
Hydroxypropyl Methylcellulose is generally stable in the pH 3–11 range.
What ingredients are compatible with Hydroxypropyl Methylcellulose?
Hydroxypropyl Methylcellulose works well with Glycerin, Propylene Glycol, Carbomer, Sodium Hyaluronate, Panthenol, Niacinamide. Use caution when combining it with High concentrations of electrolytes, Strongly oxidizing agents.
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- Hydroxypropyl Starch PhosphateThickener
- Ammonium Acryloyldimethyltaurate VP CopolymerThickener
- HydroxyethylcelluloseThickener