At a glance
- CAS number
- 104-29-0
- INCI name
- Chlorphenesin
- Function
- preservative, antimicrobial
- Typical use level
- 0.1%–0.3%
- Solubility
- both
- Stable pH
- 3–8
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
chlorphenesin 3-(4-Chlorophenoxy)-1,2-propanediol 3-(4-chlorophenoxy)propane-1,2-diol Chlorphenesinum Chlorphenesine Clorfenesina 1,2-Propanediol, 3-(4-chlorophenoxy)- 3-(p-Chlorophenoxy)-1,2-propanediol Glycerol alpha-p-chlorophenyl ether p-Chlorophenyl-alpha-glyceryl ether 3-(p-Chlorophenoxy)propane-1,2-diol RefChem:57031
Compatibility
Works well with:
Phenoxyethanol Ethylhexylglycerin Caprylyl Glycol Glycerin Propylene Glycol Niacinamide Hyaluronic Acid Carbomer Xanthan Gum
Use caution with:
High-concentration Cationic Surfactants Nonionic Surfactants (high HLB, high concentration)
Chlorphenesin is commonly paired with phenoxyethanol or caprylyl glycol for broad-spectrum preservation with potential reduction in individual use levels. High concentrations of nonionic or cationic surfactants can reduce its antimicrobial efficacy through micellar entrapment. It is generally stable across a wide pH range, making it versatile in many formulation types.
Formulation notes
EU Cosmetics Regulation limits use to a maximum of 0.3% in rinse-off and leave-on products. Primarily effective against gram-negative bacteria and fungi; often combined with other preservatives for full-spectrum coverage. Not approved for use in products intended for children under 3 in some jurisdictions — check local regulations.
Frequently asked questions
What is Chlorphenesin?
Chlorphenesin is a preservative, antimicrobial used in cosmetic and personal-care formulation. Typical use level is 0.1%–0.3%. It is both-soluble. Stable in the pH 3–8 range.
What is Chlorphenesin used for?
Chlorphenesin is used as preservative, antimicrobial in cosmetic and personal-care formulations.
What is the typical use level of Chlorphenesin?
Chlorphenesin is typically used at 0.1%–0.3% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Chlorphenesin?
The CAS registry number for Chlorphenesin is 104-29-0. Its INCI name is Chlorphenesin.
At what pH is Chlorphenesin stable?
Chlorphenesin is generally stable in the pH 3–8 range.
What ingredients are compatible with Chlorphenesin?
Chlorphenesin works well with Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol, Glycerin, Propylene Glycol, Niacinamide, Hyaluronic Acid, Carbomer, Xanthan Gum. Use caution when combining it with High-concentration Cationic Surfactants, Nonionic Surfactants (high HLB, high concentration).
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