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Undecylenoyl Phenylalanine

Undecylenoyl Phenylalanine is a skin brightening, depigmenting agent, melanogenesis inhibitor used in cosmetic and personal-care formulation. Typical use level is 0.1%–5%. It is oil-soluble. Stable in the pH 4–7.5 range.

At a glance

CAS number
175357-18-3
INCI name
Undecylenoyl Phenylalanine
Function
skin brightening, depigmenting agent, melanogenesis inhibitor
Typical use level
0.1%–5%
Solubility
oil
Stable pH
4–7.5

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

Sepiwhite MSH N-undecylenoyl-L-phenylalanine undecylenic acid phenylalanine conjugate

Compatibility

Works well with:
Niacinamide Ascorbyl Glucoside Alpha-Arbutin Kojic Acid Glycerin Tocopherol

Generally well tolerated alongside other skin-brightening actives such as niacinamide and arbutin, allowing for combination brightening formulas. Being lipophilic, it requires solubilization in an emollient or emulsifier system before incorporation into water-continuous emulsions. No widely documented severe incompatibilities, though oxidative conditions or very high pH may reduce efficacy.

Formulation notes

Undecylenoyl Phenylalanine is a lipophilic amino acid derivative that reduces melanin synthesis by competitively inhibiting the binding of alpha-MSH (melanocyte-stimulating hormone) to its receptor (MC1-R), thereby decreasing tyrosinase activity and pigment production. It is used in brightening, anti-spot, and even-tone formulations, often marketed under the trade name Sepiwhite MSH. It is considered a non-cytotoxic alternative to hydroquinone and is generally well tolerated at concentrations up to 5% in leave-on products.

Frequently asked questions

What is Undecylenoyl Phenylalanine?

Undecylenoyl Phenylalanine is a skin brightening, depigmenting agent, melanogenesis inhibitor used in cosmetic and personal-care formulation. Typical use level is 0.1%–5%. It is oil-soluble. Stable in the pH 4–7.5 range.

What is Undecylenoyl Phenylalanine used for?

Undecylenoyl Phenylalanine is used as skin brightening, depigmenting agent, melanogenesis inhibitor in cosmetic and personal-care formulations.

What is the typical use level of Undecylenoyl Phenylalanine?

Undecylenoyl Phenylalanine is typically used at 0.1%–5% in the finished formulation. Always confirm against your supplier's technical data sheet.

What is the CAS number of Undecylenoyl Phenylalanine?

The CAS registry number for Undecylenoyl Phenylalanine is 175357-18-3. Its INCI name is Undecylenoyl Phenylalanine.

At what pH is Undecylenoyl Phenylalanine stable?

Undecylenoyl Phenylalanine is generally stable in the pH 4–7.5 range.

What ingredients are compatible with Undecylenoyl Phenylalanine?

Undecylenoyl Phenylalanine works well with Niacinamide, Ascorbyl Glucoside, Alpha-Arbutin, Kojic Acid, Glycerin, Tocopherol.

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