At a glance
- CAS number
- 100403-19-8
- INCI name
- Ceramide NP
- Function
- barrier repair, emollient, skin-identical ingredient, moisturizer
- Typical use level
- 0.01%–2%
- Solubility
- oil
- Stable pH
- 4–7
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
Ceramide 3 N-stearoylphytosphingosine Ceramide III Phytoceramide
Compatibility
Works well with:
Cholesterol Fatty Acids Ceramide AP Ceramide EOP Niacinamide Hyaluronic Acid
Ceramide NP works synergistically with cholesterol and free fatty acids to mimic the natural skin lipid matrix, typically in a molar ratio of 1:1:1 or 3:1:1 ceramide:cholesterol:fatty acid. It is best delivered via a lamellar emulsion system or liposomal encapsulation to maximize skin penetration and efficacy. Avoid high-temperature processing above 70°C for extended periods to prevent degradation.
Formulation notes
Ceramide NP is a skin-identical ceramide naturally found in the stratum corneum, where it plays a critical role in maintaining the skin barrier and reducing transepidermal water loss. Formulators use it to restore lipid barrier integrity in dry, compromised, or sensitive skin, making it a key active in moisturizers, barrier creams, and eczema-targeted products. Because it is lipophilic and waxy, it typically requires solubilization in a carrier oil or emulsifier system before incorporation.
Frequently asked questions
What is Ceramide NP?
Ceramide NP is a barrier repair, emollient, skin-identical ingredient, moisturizer used in cosmetic and personal-care formulation. Typical use level is 0.01%–2%. It is oil-soluble. Stable in the pH 4–7 range.
What is Ceramide NP used for?
Ceramide NP is used as barrier repair, emollient, skin-identical ingredient, moisturizer in cosmetic and personal-care formulations.
What is the typical use level of Ceramide NP?
Ceramide NP is typically used at 0.01%–2% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Ceramide NP?
The CAS registry number for Ceramide NP is 100403-19-8. Its INCI name is Ceramide NP.
At what pH is Ceramide NP stable?
Ceramide NP is generally stable in the pH 4–7 range.
What ingredients are compatible with Ceramide NP?
Ceramide NP works well with Cholesterol, Fatty Acids, Ceramide AP, Ceramide EOP, Niacinamide, Hyaluronic Acid.
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