Isopropyl Myristate

At a glance

CAS number

110-27-0

INCI name

Isopropyl Myristate

Function

emollient, solvent, penetration enhancer, binder, skin conditioning agent

Typical use level

1%–15%

Solubility

oil

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

Isopropyl tetradecanoate Isomyst Bisomel Estergel Tetradecanoic acid, 1-methylethyl ester Deltyl Extra propan-2-yl tetradecanoate Kesscomir Promyr Crodamol IPM Tegester Wickenol 101

Compatibility

Works well with:
Dimethicone Cyclopentasiloxane Mineral Oil Caprylic/Capric Triglyceride Cetyl Alcohol Stearyl Alcohol Beeswax Shea Butter Jojoba Oil Squalane

Use caution with:
High-concentration Niacinamide Strong oxidizing agents

Isopropyl Myristate is broadly compatible with most oil-phase ingredients and silicones. At higher concentrations it may be comedogenic for acne-prone skin, and its penetration-enhancing properties can increase dermal absorption of co-formulated actives, which should be considered for safety assessments. Compatibility with oxidizing agents is poor as it can undergo oxidative degradation.

Formulation notes

Generally recognized as safe at typical use levels (1–15%); however, comedogenicity potential limits use in products targeting acne-prone skin. Its penetration-enhancing effect means co-formulated actives (e.g., retinoids, corticosteroids) may show increased absorption — evaluate accordingly. No specific regulatory concentration cap in major markets, but use at minimum effective level.

Frequently asked questions

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